Sunday, February 13, 2011

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Benefits of supplementation with acetyl-L-carnitine on brain function:



When acetylcholine levels begin to decline as a result of the aging process, supplementing with acetyl-L-carnitine can stimulate the production of acetylcholine and memory improve short-and long-term capacity of concentration and attention, hand / eye coordination, speed of reaction to stimuli and therefore cognitive function , perception, memory, opinion, reasoning, humor and emotional wellbeing.


The acetyl-L-carnitine seems to be one of the few substances capable of slowing the progression of Alzheimer's disease and improve function brain even in cases where damage is irreparable.


Recommended dose 100-500 mg. Clinical trials for the treatment of Alzheimer's and Parkinson have used doses between 1500 and 2000 mg without significant side effects were appreciated.


Dr. Iraima Acuña. Nutrition Specialist.

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Carnitine and Alzheimer's disease:



The acetylcholine is the most important and abundant neurotransmitter chemical transporter controller memory and motor skills. It is produced in significant quantities in the hippocampus (part of the brain that controls our memory.) With the aging process progressively decreases its production and therefore gradually lose the ability to concentrate on what we do and we started to forget things great and small.


The imbalance between the enzymes needed to synthesize acetylcholine and needed to metabolize it, is responsible for the marked decrease in the levels of acetylcholine that occurs in Alzheimer's disease. In the early stages of Alzheimer's disease also produces a decrease of cellular energy, making the brain less able to extract oxygen and glucose from the blood, a situation that can be reversed in patients supplemented with acetyl-L-carnitine.


has been experimentally found that supplementation with acetyl-L-carnitine in mice not only normalized energy metabolism brain cells but reversed the abnormalities caused by ammonia, which causes degeneration of brain cells similar to that found in people with Alzheimer's disease.


Dr. Iraima Acuña. Nutrition Specialist

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Carnitine and brain function:



The carnitine is an amino acid found in large quantities in meat, which derives its name. Its main action is energy production, efficiently transporting fatty acids from the cytoplasm to the mitochondria, where they burn and generate the energy needed to biological processes essential for our body.


In the form of acetyl-L-carnitine (ALC) (which is the chemical addition of an acetyl group to the natural carnitine), not only fatty acids leads efficiently to mitochondria, but the available acetyl group, promotes the production of acetylcholine , one of the most important brain neurotransmitters and is considered the "messenger of memory."


The acetyl-L-carnitine also limits the production of free radicals, protecting brain cells and slows the decline in the levels of growth factors nerve tissue that occurs as a result of the aging process. It has been found in mice that acetyl-L-carnitine delay and even reverse the degeneration factor brain-derived neurotrophic (BDNF), to help rebuild the brain and nerve tissues.


Dr. Iraima Acuña. Nutrition Specialist